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The viability of a tissue is influenced by a number
of internal and external factors such as drugs, topically applied agents and
constituents in the environment. Consequently, the physiological response to
such stimuli – hereafter denoted tissue viability - has become a concept of
ever increasing importance in skin testing, medical research and clinical
medicine. A frequently used measure of skin viability is the ability of the
dermal tissue microvascular network to react with vasodilatation (increased
blood flow) or vasoconstriction (reduced blood flow) as a response to an
allergic reaction, an inflammatory process or irritation of the skin in more
general terms.
In spite of the fact that reddening of the skin can
be seen by the naked eye, more objective measures are necessary to be able
to quantify the microvascular reaction to a topically applied substance or
the intake of a vaso-active drug. The Tissue
Vaibility Imaging technology quantifies erythema and
blanching thereby making the result of skin testing user and laboratory
independent.
The TiVi600 Tissue
Viability Imager provides a versatile solution to this
problem for the skin, the body's largest and arguably most
complex organ. Applications are found primarily in the development
of skin care products, drug development and in the assessment of potentially
hazardous agents in our environment.
The
TiVi60 Skin Damage Visualizer
facilitates quantitative work-site investigations of hand microcirculation
damage caused by i.e. chemical compounds, vibrating tools or extensive use
of protective gloves.
The
TiVi70 Skin Colour Tracker makes
it possible to map areas of colours within a user-specified colour space.
Alterations in local skin colour over time and over a surface can be
quantified and visualized.
The
TiVi80 Spot Analyzer automatically
calculates the erythema intensity and extension of facial spots. The results
can be successively uploaded into the integrated Project Window that
displays an instant overview of a test panel outcome, thereby assisting the
dermatologist in the visual scoring process.
The
TiVi90 Wrinkle Analyzer
automatically calculates vital parameters such
as wrinkle depth, volume and asymmetry. An Integrated Library and Trend
monitor assists in the assessment of the outcome of a treatment procedure.
The
TiVi95 Surface Analyzer
automatically detects and maps skin sites with
dimples characteristic of cellulite formation. An integrated Library and
Trend monitor makes it possible to follow and quantify improvement as the
result of a treatment procedure expressed as an automatically calculated
Improvement Index. A specific window allows for the investigation and
quantification of surface reflectivity.
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